Upper abdominal pain
Vague pain in the upper abdomen, sometimes extending to the right shoulder blade.
Liver cancer — most commonly hepatocellular carcinoma — often develops on the background of chronic liver disease, which makes gentle, precise treatment essential. AARO's Dr David Tan set up Singapore's pioneering liver SBRT programme at NCCS: ablative radiation delivered in five or fewer sessions.
Liver cancer is the abnormal growth of cells in the liver. The most common primary type is hepatocellular carcinoma (HCC), which begins in the hepatocytes — the liver's main cells. Less common types include cholangiocarcinoma (bile duct cancer), hepatoblastoma in young children, and hemangiosarcoma arising from the liver's blood vessels.
Metastatic cancer — disease that spreads to the liver from another origin such as the colon or breast — is actually more common than cancer that begins in the liver itself, and is a frequent target for liver-directed treatment.
Early detection matters: untreated tumours can enlarge until they rupture, disturb the liver's function, or spread through the bloodstream. High-risk patients — those with cirrhosis or chronic hepatitis B — should discuss regular surveillance with their doctor.
Early liver cancer usually causes no specific symptoms. When symptoms do emerge, they include:
Vague pain in the upper abdomen, sometimes extending to the right shoulder blade.
General tiredness that doesn't improve with rest.
Losing weight or appetite without explanation.
A mass or fluid build-up causing the abdomen to swell.
Yellowing of the skin and the whites of the eyes.
Persistent itching, often related to bile salt build-up.
For high-risk patients, surveillance catches liver cancer while it's small — when survival is higher and every treatment option remains open.
Alpha-fetoprotein is a tumour marker often raised in liver cancer — a signal for further investigation rather than a diagnosis by itself.
Surveillance ultrasound detects abnormalities in the liver, especially in cirrhotic or hepatitis-B patients under regular screening.
Multiphase CT and MRI characterise the lesion — in many cases confirming HCC by imaging alone.
When imaging is inconclusive, a biopsy confirms the diagnosis and grade.
Liver cancer usually develops on a background of chronic liver damage — much of which is preventable.
Chronic viral hepatitis is the leading cause. Hepatitis B is vaccine-preventable; both warrant surveillance once chronic.
Scarring of the liver from any cause substantially raises risk.
Long-term alcohol abuse damages the liver and drives cirrhosis.
A toxin produced by mould on poorly stored peanuts and grains.
Diabetes and metabolic fatty liver disease are increasingly common contributors.
A relative with liver cancer raises your own risk.
Treatment depends on the tumour's stage, the liver's underlying health, and your overall condition — decided in multidisciplinary discussion. Radiation now plays a curative role that barely existed a decade ago.
Ablative radiation in five or fewer sessions — non-invasive, precise, and effective for HCC and liver metastases. Our specialist set up Singapore's pioneering programme.
Breath-hold and motion-management techniques track the liver as it moves with breathing, keeping healthy liver out of the beam.
Modern systemic options for advanced HCC, coordinated within your overall plan.
Surgery, ablation, embolisation (TACE) and transplant assessment — AARO coordinates radiation within the full toolkit, including an international trial comparing SBRT with TACE.
Every plan at AARO goes through detailed contouring, dose simulation, and independent physics review before a single beam is delivered. We do this so the radiation hits exactly the tissue that needs it — and avoids the healthy tissue around it.
Our medical physicists and radiation therapists collaborate on each plan — contouring tumour and organs-at-risk, simulating dose distribution, and independently checking every parameter before delivery.
Imaging before each fraction confirms the target's position to the millimetre — so tight margins stay safe, and healthy tissue stays out of the high-dose region.
Each treatment session takes 15–30 minutes. You'll lie on a precision treatment couch beneath the linear accelerator. Positioning lasers and daily imaging align you to within a millimetre of the planned position.
You won't feel the radiation as it's delivered. There's no anaesthesia, no recovery time, and no overnight stay. Most patients drive themselves home after the session and return to normal activities the same day.
Liver-directed radiation at AARO is led by the specialist who established Singapore's liver SBRT programme and co-investigates international liver SBRT trials.
Book a 45–60 minute specialist consultation. We'll review your imaging and pathology, explain the options that apply to your case, and answer your questions.